PROXIMA-2A

Ru and Rh binding sites in the structure of human serum transferrin with Fe3+ bound at the C-lobe

Référence
A.-S. Banneville, G. Ferraro, R. D'Elia, I. Cornaciu-Hoffmann, A. Pica, A. Merlino "Ru and Rh binding sites in the structure of human serum transferrin with Fe3+ bound at the C-lobe". Dalton Transactions, 55():4051-4056. (2026).
Année de publication
2026
Auteurs
A.-S. Banneville
G. Ferraro
R. D'Elia
I. Cornaciu-Hoffmann
A. Pica
A. Merlino
Lignes de lumière
rec-number
12961
Référence anonyme
A.-S. Banneville, G. Ferraro, R. D'Elia, I. Cornaciu-Hoffmann, A. Pica, A. Merlino "Ru and Rh binding sites in the structure of human serum transferrin with Fe3+ bound at the C-lobe". Dalton Transactions, 55():4051-4056. (2026).
Type de publication
Date

Neutron Crystallography Study of Host–Pathogen Recognition Enhanced by Hydrogen/Deuterium Exchange on Carbohydrates

Référence
T. Arnaud, C. Tatol, J. M. Devos, L. Gajdos, S. Vidal, M. Korsak, A. Varrot, M. Wimmerova, S. Feuillastre, M. P. Blakeley, A. Imberty "Neutron Crystallography Study of Host–Pathogen Recognition Enhanced by Hydrogen/Deuterium Exchange on Carbohydrates". Chemistry Europe, 4(3):e202500424. (2026).
Année de publication
2026
Auteurs
T. Arnaud
C. Tatol
J. M. Devos
L. Gajdos
S. Vidal
M. Korsak
A. Varrot
M. Wimmerova
S. Feuillastre
M. P. Blakeley
A. Imberty
Lignes de lumière
rec-number
13014
Référence anonyme
T. Arnaud, C. Tatol, J. M. Devos, L. Gajdos, S. Vidal, M. Korsak, A. Varrot, M. Wimmerova, S. Feuillastre, M. P. Blakeley, A. Imberty "Neutron Crystallography Study of Host–Pathogen Recognition Enhanced by Hydrogen/Deuterium Exchange on Carbohydrates". Chemistry Europe, 4(3):e202500424. (2026).
Type de publication
Date

Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis

Référence
Z. Edoo, C. Grosse, T. Maitre, R. Frita, A. Chauffour, L. Fournier Le Ray, A. Godmer, A. Aubry, M. Bourotte, R. Antoine, L. Tawk, S. Slupek, V. Trebosc, B. Schellhorn, A. Dreneau, L. Hofmann, C. Kemmer, S. Lociuro, G. E. Dale, F. Jung, E. Pérez-Herrán, A. Mendoza, M. J. Rebollo López, S. Ghidelli-Disse, T. Werner, L. Ballell, D. Barros-Aguirre, V. Mathys, K. Soetaert, V. Megalizzi, R. Wintjens, M. Gitzinger, B. Deprez, N. Veziris, M. J. Remuiñán, N. Willand, M. Pieren, A. R. Baulard "Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis". Nature Communications, 17():4954. (2026).
Année de publication
2026
Auteurs
Z. Edoo
C. Grosse
T. Maitre
R. Frita
A. Chauffour
L. Fournier Le Ray
A. Godmer
A. Aubry
M. Bourotte
R. Antoine
L. Tawk
S. Slupek
V. Trebosc
B. Schellhorn
A. Dreneau
L. Hofmann
C. Kemmer
S. Lociuro
G. E. Dale
F. Jung
E. Pérez-Herrán
A. Mendoza
M. J. Rebollo López
S. Ghidelli-Disse
T. Werner
L. Ballell
D. Barros-Aguirre
V. Mathys
K. Soetaert
V. Megalizzi
R. Wintjens
M. Gitzinger
B. Deprez
N. Veziris
M. J. Remuiñán
N. Willand
M. Pieren
A. R. Baulard
Lignes de lumière
rec-number
13064
Référence anonyme
Z. Edoo, C. Grosse, T. Maitre, R. Frita, A. Chauffour, L. Fournier Le Ray, A. Godmer, A. Aubry, M. Bourotte, R. Antoine, L. Tawk, S. Slupek, V. Trebosc, B. Schellhorn, A. Dreneau, L. Hofmann, C. Kemmer, S. Lociuro, G. E. Dale, F. Jung, E. Pérez-Herrán, A. Mendoza, M. J. Rebollo López, S. Ghidelli-Disse, T. Werner, L. Ballell, D. Barros-Aguirre, V. Mathys, K. Soetaert, V. Megalizzi, R. Wintjens, M. Gitzinger, B. Deprez, N. Veziris, M. J. Remuiñán, N. Willand, M. Pieren, A. R. Baulard "Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis". Nature Communications, 17():4954. (2026).
Type de publication
Date

25-nitro-20-epi-vitamin D analogue with anti-proliferative and cytoprotective properties: Biological and pharmacological evaluation

Référence
U. Gómez-Bouzó, C. Peluso-Iltis, S. Barreiro, C. Fernandes, L. Verlinden, A. Verstuyf, F. Borge, N. Rochel, G. Gómez, Y. Fall "25-nitro-20-epi-vitamin D analogue with anti-proliferative and cytoprotective properties: Biological and pharmacological evaluation". Experimental and Molecular Pathology, 145():105036. (2026).
Année de publication
2026
Auteurs
U. Gómez-Bouzó
C. Peluso-Iltis
S. Barreiro
C. Fernandes
L. Verlinden
A. Verstuyf
F. Borge
N. Rochel
G. Gómez
Y. Fall
Lignes de lumière
rec-number
13072
Référence anonyme
U. Gómez-Bouzó, C. Peluso-Iltis, S. Barreiro, C. Fernandes, L. Verlinden, A. Verstuyf, F. Borge, N. Rochel, G. Gómez, Y. Fall "25-nitro-20-epi-vitamin D analogue with anti-proliferative and cytoprotective properties: Biological and pharmacological evaluation". Experimental and Molecular Pathology, 145():105036. (2026).
Type de publication
Date

The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms

Référence
Z. Marouf,, C. Tellier-Lebegue,, M. Glousieau,, N. Morellet,, P. Cuniasse,, A. Bourand-Plantefol,, S. Plancqueel,, I. Mahmoudi,, J. Andreani,, P. Legrand,, V. Ropars,, R. Ruedas,, L.-F.Hermouet,, M. Moutiez,, N. Nhiri,, M. Fonvielle,, S. Bressanelli,, T. Katoh,, P. Fernandez Varela,, E. Lescop,, J.-B. Charbonnier,, M. Gondry "The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms". Nucleic Acids Research, 54(6):. (2026).
Année de publication
2026
Auteurs
Z. Marouf,
C. Tellier-Lebegue,
M. Glousieau,
N. Morellet,
P. Cuniasse,
A. Bourand-Plantefol,
S. Plancqueel,
I. Mahmoudi,
J. Andreani,
P. Legrand,
V. Ropars,
R. Ruedas,
L.-F.Hermouet,
M. Moutiez,
N. Nhiri,
M. Fonvielle,
S. Bressanelli,
T. Katoh,
P. Fernandez Varela,
E. Lescop,
J.-B. Charbonnier,
M. Gondry
Lignes de lumière
rec-number
13068
Référence anonyme
Z. Marouf,, C. Tellier-Lebegue,, M. Glousieau,, N. Morellet,, P. Cuniasse,, A. Bourand-Plantefol,, S. Plancqueel,, I. Mahmoudi,, J. Andreani,, P. Legrand,, V. Ropars,, R. Ruedas,, L.-F.Hermouet,, M. Moutiez,, N. Nhiri,, M. Fonvielle,, S. Bressanelli,, T. Katoh,, P. Fernandez Varela,, E. Lescop,, J.-B. Charbonnier,, M. Gondry "The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms". Nucleic Acids Research, 54(6):. (2026).
Type de publication
Date

Structure-Based Discovery of Imidazo[4,5-c]pyridine SARM1 Modulators Showing Paradoxical Activation

Référence
S. K. Albanese, B. E. Hopkins, A. M. Olland, A. Fairman, N. Shaikh, S. Feng, M. Thakkar, A. Verras, A. Dementiev, W. G. Walkup 4th, C. Atsriku, H. D. Srinivas, W. Allen, K. Ashraf, P. H. Bos, P. Hsiao, K. Kroeck, Z. Liu, A. Nagarajan, C. T. Szlenk, M. Svensson, Z. Lee Johnson, K. Kapilashrami, S. Rubino, A. Kaplan, A. M. Levinson "Structure-Based Discovery of Imidazo[4,5-c]pyridine SARM1 Modulators Showing Paradoxical Activation". Journal of Medicinal Chemistry, 69(8):9521-9536. (2026).
Année de publication
2026
Auteurs
S. K. Albanese
B. E. Hopkins
A. M. Olland
A. Fairman
N. Shaikh
S. Feng
M. Thakkar
A. Verras
A. Dementiev
W. G. Walkup 4th
C. Atsriku
H. D. Srinivas
W. Allen
K. Ashraf
P. H. Bos
P. Hsiao
K. Kroeck
Z. Liu
A. Nagarajan
C. T. Szlenk
M. Svensson
Z. Lee Johnson
K. Kapilashrami
S. Rubino
A. Kaplan
A. M. Levinson
Lignes de lumière
rec-number
13099
Référence anonyme
S. K. Albanese, B. E. Hopkins, A. M. Olland, A. Fairman, N. Shaikh, S. Feng, M. Thakkar, A. Verras, A. Dementiev, W. G. Walkup 4th, C. Atsriku, H. D. Srinivas, W. Allen, K. Ashraf, P. H. Bos, P. Hsiao, K. Kroeck, Z. Liu, A. Nagarajan, C. T. Szlenk, M. Svensson, Z. Lee Johnson, K. Kapilashrami, S. Rubino, A. Kaplan, A. M. Levinson "Structure-Based Discovery of Imidazo[4,5-c]pyridine SARM1 Modulators Showing Paradoxical Activation". Journal of Medicinal Chemistry, 69(8):9521-9536. (2026).
Type de publication
Date

Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure

Référence
R. Nermont, S. Oueslati, M. Aumont-Nicaise, P. Retailleau, B. I. Iorga, T. Naas "Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure". Antimicrobial Agents and Chemotherapy, 70(6):. (2026).
Année de publication
2026
Auteurs
R. Nermont
S. Oueslati
M. Aumont-Nicaise
P. Retailleau
B. I. Iorga
T. Naas
Lignes de lumière
rec-number
13112
Référence anonyme
R. Nermont, S. Oueslati, M. Aumont-Nicaise, P. Retailleau, B. I. Iorga, T. Naas "Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure". Antimicrobial Agents and Chemotherapy, 70(6):. (2026).
Type de publication
Date

Du 16 au 20 mars 2026, 24 jeunes scientifiques venus du monde entier sont accueillis au Synchrotron SOLEIL pour une semaine de formation intensive dans le cadre de l’école européenne HERCULES (Higher European Research Course of User of Large Experimental Systems).

New fluoxetine analogues as anti-enterovirus agents targeting 2C protein

Référence
Khemiri, S., Faucher, M.O., Bourg, S., Attoumani-Madi, S., Yaacoub, C., Touret, F., Farag, M., Fermiana Vitorino, M., Bonnet c, Vanelle, P., Aci-Seche, S., Coutard, B., Barral, K. "New fluoxetine analogues as anti-enterovirus agents targeting 2C protein". European Journal of Inorganic Chemistry, 306():118621. (2026).
Année de publication
2026
Auteurs
Khemiri, S.
Faucher, M.O.
Bourg, S.
Attoumani-Madi, S.
Yaacoub, C.
Touret, F.
Farag, M.
Fermiana Vitorino, M.
Bonnet c
Vanelle, P.
Aci-Seche, S.
Coutard, B.
Barral, K.
Lignes de lumière
rec-number
12889
Référence anonyme
Khemiri, S., Faucher, M.O., Bourg, S., Attoumani-Madi, S., Yaacoub, C., Touret, F., Farag, M., Fermiana Vitorino, M., Bonnet c, Vanelle, P., Aci-Seche, S., Coutard, B., Barral, K. "New fluoxetine analogues as anti-enterovirus agents targeting 2C protein". European Journal of Inorganic Chemistry, 306():118621. (2026).
Type de publication
Date

Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis

Référence
Carloni, G., Gaday, Q., Megrian, D., Petit, J., Martinez, M., Sogues, A., Ben Assaya, M., Kakonyi, M., Haouz, A., Alzari, P.M., Wehenkel, A.M. "Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis". MBio, 17(3):e03700-25. (2026).
Année de publication
2026
Auteurs
Carloni, G.
Gaday, Q.
Megrian, D.
Petit, J.
Martinez, M.
Sogues, A.
Ben Assaya, M.
Kakonyi, M.
Haouz, A.
Alzari, P.M.
Wehenkel, A.M.
Lignes de lumière
rec-number
12890
Référence anonyme
Carloni, G., Gaday, Q., Megrian, D., Petit, J., Martinez, M., Sogues, A., Ben Assaya, M., Kakonyi, M., Haouz, A., Alzari, P.M., Wehenkel, A.M. "Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis". MBio, 17(3):e03700-25. (2026).
Type de publication
Date