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Flexibility-frustrated porosity for enhanced selective CO2 adsorption in an ultramicroporous metal-organic framework
Publié le 07/01/2025
... Chen, X., Menon, D., Wang, X., He, M., Kiapi, M.R.A., Asgari, M., Lyu, X., Tang, X., Keenan, L.L., Shepard, W., Wee, L.H., Yang, S., Farha, O.K., Fairen-Jimenez, D. "Flexibility-frustrated porosity for enhanced selective CO2 adsorption in an ...
Structure-Based Discovery of a Series of Covalent, Orally Bioavailable, and Selective BFL1 Inhibitors
Publié le 10/12/2024
... Palisse, A., Cheung, T., Blokhuis, A., Cogswell, T., Martins, B.S., Riemens, R., Schellekens, R., Battocchio, G., Jansen, C., Cottee, M.A., Ornell, K., Sacchetto, C., Leon, L., van Hoek-Emmelot, M., Bostock, M., Brauer, B.L., Beaumont, K., Lucas, S.C.C., ...
Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties
Publié le 04/12/2024
... Redeghieri, P., Moray, J., Kerff, F., Gohy S., Leal, T., Muyldermans, S., Vanbever, R., Morales-Yánez, F.J., Dumoulin, M. "Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting ...
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Publié le 04/12/2024
... Loureiro, J., Seoane, S., Sampaio-Dias, I.E., Peluso-Iltis, C., Guiberteau, T., Brito, B., Gregorio, C., Pérez-Fernández, R., Rochel, N., Mouriño, A., Rodríguez-Borges, J.E. "First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and ...
Thioredoxin 1 moonlights as a chaperone for an interbacterial ADP-ribosyltransferase toxin
Publié le 04/12/2024
... Dumont, B., Terradot, L., Cascales, E., Van Melderen, L., Jurėnas, D. "Thioredoxin 1 moonlights as a chaperone for an interbacterial ADP-ribosyltransferase toxin" Nature Communications., 15: art.n° 10388. (2024). ...
Synthesis, structural elucidation, and DNA binding behavior of a ternary copper(II) complex featuring substituted bipyridyl and dicarboxylate ligands
Publié le 28/11/2024
... Rahaman, S.K., Chatterjee, T., Shaikh, K., Khan, S., Siddiqui, M.R., Wabaidur, S.M., Islam, M.M., Alam, S.M., Mir, M.H. "Synthesis, structural elucidation, and DNA binding behavior of a ternary copper(II) complex featuring substituted bipyridyl and ...
A Macrocycle-Mediated Protein Cage
Publié le 28/11/2024
... Flood, R.J., Thureau, A., Crowley, P.B. "A Macrocycle-Mediated Protein Cage" ACS Macro Letters., 13(12): 1686–1690. (2024). ...
Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies
Publié le 28/11/2024
... Cecil, A.J., Sogues, A., Gurumurthi, M., Lane, K.S., Remaut, H., Pak, A.J. "Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies" PNAS Nexus., 3(12): art.n° pgae538. (2024). ...
Dimerization of ADAR1 modulates site-specificity of RNA editing
Publié le 22/11/2024
... Mboukou, A., Rajendra, V., Messmer, S., Mandl, T.C., Catala, M., Tisné, C., Jantsch, M.F., Barraud, P. "Dimerization of ADAR1 modulates site-specificity of RNA editing" Nature Communications., 15: art.n° 10051. (2024). ...
Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands
Publié le 05/11/2024
... Antonini, G., Bernardi, A., Gillon, E., Dal Corso, A., Civera, M., Belvisi, L., Varrot, A., Mazzotta, S. "Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands" Journal of Medicinal Chemistry., 67(21): 19546-19560. (2024). ...