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Biochemical and Structural Characterization of Chi-Class Glutathione Transferases: A Snapshot on the Glutathione Transferase Encoded by sll0067 Gene in the Cyanobacterium Synechocystis sp. Strain PCC 6803
Publié le 13/10/2022
... Mocchetti, E., Morette, L., Mulliert, G., Mathiot, S., Guillot, B., Dehez, F., Chauvat, F., Cassier-Chauvat, C., Brochier-Armanet, C., Didierjean, C., Hecker, A. "Biochemical and Structural Characterization of Chi-Class Glutathione Transferases: A ...
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs
Publié le 13/10/2022
... Green, S.R., Davis, S.H., Damerow, S., Engelhart, C.A., Mathieson, M., Baragaña, B., Robinson, D.A., Tamjar, J., Dawson, A., Tamaki, F.K., Buchanan, K.I., Post, J., Dowers, K., Shepherd, S.M., Jansen, C., Zuccotto, F., Gilbert, I.H., Epemolu, O., Riley, J ...
Targeting non-alcoholic fatty liver disease: Design, X-ray co-crystal structure and synthesis of ‘first-in-kind’ inhibitors of serine/threonine kinase25
Publié le 12/10/2022
... Kiyeleko, S., Hocine, S., Mautino, G., Kuenemann, M., Nawrotek, A., Miallau, L., Vuillard, L.M., Mirguet, O., Kotschy, A., Hanessian, S. "Targeting non-alcoholic fatty liver disease: Design, X-ray co-crystal structure and synthesis of ‘first-in-kind’ ...
Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis
Publié le 07/10/2022
... Barelier, S., Avellan, R., Gnawali, G.R., Fourquet, P., Roig-Zamboni, V., Poncin, I., Point, V., Bourne, Y., Audebert, S., Camoin, L., Spilling, C.D., Canaan, S., Cavalier, J.F., Sulzenbacher, G. "Direct capture, inhibition and crystal structure of HsaD ...
Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia’s BC2L-C Lectin
Publié le 30/09/2022
... Bermeo, R., Lal, K., Ruggeri, D., Lanaro, D., Mazzotta, S., Vasile, F., Imberty, A., Belvisi, L., Varrot, A., Bernardi, A. "Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia’s BC2L-C Lectin" ACS Chemical ...
Structural and large-scale analysis unveil the intertwined paths promoting NMT-catalyzed lysine and glycine myristoylation
Publié le 29/09/2022
... Rivière, F., Dian, C., Dutheil, R.F., Monassa, P., Giglione, C., Meinnel, T. "Structural and large-scale analysis unveil the intertwined paths promoting NMT-catalyzed lysine and glycine myristoylation" Journal of Molecular Biology., 434(22): art.n° ...
Adaptive Binding of Alkyl Glycosides by Nonpeptidic Helix Bundles in Water: Toward Artificial Glycolipid Binding Proteins
Publié le 22/09/2022
... Yoo, S.H., Buratto, J., Roy, A., Morvan, E., Pasco, M., Pulka-Ziach, K., Lombardo, C.M., Rosu, F., Gabelica, V., Mackereth, C.D., Collie, G.W., Guichard, G. "Adaptive Binding of Alkyl Glycosides by Nonpeptidic Helix Bundles in Water: Toward Artificial ...
Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip
Publié le 20/09/2022
... Pang, L., Zanki, V., Strelkov, S.V., Van Aerschot, A., Gruic-Sovulj, I., Weeks, S.D. "Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip" Communications Biology., 5: art.n° 883. (2022). ...
The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3
Publié le 20/09/2022
... Notova, S., Bonnardel , F., Rosato, F., Siukstaite, L., Schwaiger, J., Lim, J.H., Bovin, N., Varrot, A., Ogawa, Y., Römer, W., Lisacek, F., Imberty, A. "The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor ...
Quantitative fragmentomics allow affinity mapping of interactomes
Publié le 20/09/2022
... Gogl, G., Zambo, B., Kostmann, C., Cousido-Siah, A., Morlet, B., Durbesson, F., Negroni, L., Eberling, P., Jané, P., Nominé, Y., Zeke, A., Østergaard, S., Monsellier, E., Vincentelli, R., Travé, G. "Quantitative fragmentomics allow affinity mapping of ...