RECHERCHER
Résultats de la recherche ""
Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states
Publié le 13/01/2022
... Takahashi, D.T., Gadelle, D., Agama, K., Kiselev, E., hang, H., Yab, E., Petrella, S., Forterre, P., Pommier, Y., Mayer, C. "Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states" Nature Communications., 13: art.n° 59. ...
B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner
Publié le 13/01/2022
... Stein, A., Hilken née Thomopoulou, P., Frias, C.., Hopff, S.M., Varela, P., Wilke, N., Mariappan, A., Neudörfl, J.M., Fedorov, A.Y., Gopalakrishnan, J., Gigant, B., Prokop, A., Schmalz, H.G. "B-nor-methylene Colchicinoid PT-100 Selectively Induces ...
Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps
Publié le 13/01/2022
... Plé, C., Tam, H.K., Vieira Da Cruz, A., Compagne, N., Jiménez-Castellanos, J.C., Müller, R.T., Pradel, E., Foong, W.E., Malloci, G., Ballée, A., Kirchner, M.A., Moshfegh, P., Herledan, A., Herrmann, A., Deprez, B., Willand, N., Vargiu, A.V., Pos, K.M., ...
Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives
Publié le 13/01/2022
... Kostyuk, A.I., Tossounian, M.A., Panova, A.S., Thauvin, M., Raevskii, R.I., Ezeriņa,D., Wahni,K., Van Molle,I., Sergeeva,A.D., Vertommen,D., Gorokhovatsky,A.Y., Baranov,M.S., Vriz,S., Messens,J., Bilan, D.S., Belousov, V.V. "Hypocrates is a genetically ...
Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA binding site
Publié le 11/01/2022
... Goh, B.C., Xiang, X., Lescar, J., Dedon, P.C. "Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA binding site" Journal of Biological Chemistry., 298(2): art.n° 101571. (2022). ...
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex
Publié le 07/01/2022
... Hurdiss, D.L., El Kazzi, P., Bauer, L., Papageorgiou, N., Ferron, F.P., Donselaar, T., van Vliet, A.L.W., Shamorkina, T.M., Snijder, J., Canard, B., Decroly, E., Brancale, A., Ben-Mordehai, T.Z., Förster, F., van Kuppeveld, F.J.M., Coutard, B. "Fluoxetine ...
Elucidating the Structural and Minimal Protective Epitope of the Serogroup X Meningococcal Capsular Polysaccharide
Publié le 05/01/2022
... Pietri, G.P., Tontini, M., Brogioni, B., Oldrini, D., Robakiewicz, S., Henriques, P., Calloni, I., Abramova, V., Santini, L., Malić, S., Miklić, K., Lisnic, B., Bertuzzi, S., Unione, L., Balducci, E., de Ruyck, J., Romano, M.R., Jimenez-Barbero, J., ...
Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site
Publié le 05/01/2022
... Mirgaux, M., Leherte, L., Wouters, J. "Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site" International Journal of Tryptophan Research., 14(1-11): (2021). ...
Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2
Publié le 23/12/2021
... Marek, M., Ramos-Morales, E., Picchi-Constante, G.F.A., Bayer, T., Norström, C., Herp, D., Sales-Junior, P.A., Guerra-Slompo, E.P., Hausmann, K., Chakrabarti, A., Shaik, T.B., Merz, A., Troesch, E., Schmidtkunz, K., Goldenberg, S., Pierce, R.J., Mourao, M ...
Exploring the permeation of fluoroquinolone metalloantibiotics across outer membrane porins by combining molecular dynamics simulations and a porin-mimetic in vitro model
Publié le 10/12/2021
... Sousa, C.F., Coimbra, J.T.S., Richter, R., Morais-Cabral, J.H., Ramos, M.J., Lehr, C.M., Fernandes, P.A., Gameiro, P. "Exploring the permeation of fluoroquinolone metalloantibiotics across outer membrane porins by combining molecular dynamics simulations ...