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Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Publié le 21/05/2025
... Martin, E., Giakoumakis, D., Paesmans, J., Bisi, N., Drozdzecki, A., Audenaert, D., Haustraete, J., Verstreken, P., Galicia, C., Ballet, S., Versées, W. "Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity" ACS ...
Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A Biophysical Study
Publié le 29/04/2025
... Antonini, G., Fares, M., Hauck, D., Mała, P., Gillon, E., Belvisi, L., Bernardi, A., Titz, A., Varrot, A., Mazzotta, S. "Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa–Burkholderia cenocepacia Infections: A ...
Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3
Publié le 25/04/2025
... Seoane, S., Gogoi, P., Zárate-Ruíz, A., Peluso-Iltis, C., Peters, S., Guiberteau, T., Maestro, M.A., Pérez-Fernández, R., Rochel, N., Mouriño, A. "Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring ...
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase
Publié le 17/04/2025
... Kuki, Walmsley, D.L., Kanai, K., Takechi, S., Yoshida, M., Murakami, R., Takano, K., Tominaga, Y., Takahashi, M., Ito, S., Nakao, N., Angove, H., Baker, L.M., Carter, E., Dokurno, P., Le Strat, L., Macias, A.T., Molyneaux, C.A., Murray, J.B., Surgenor, A ...
N-Terminal Protein Complexation and Assembly with a Triangular Sulfated Macrocycle
Publié le 11/04/2025
... Ifeagwu, M.C., Guo, L., Mockler, N.M., Dong, M., Li, C., Crowley, P.B. "N-Terminal Protein Complexation and Assembly with a Triangular Sulfated Macrocycle" Crystal Growth & Design., 25(13): 4661-4665. (2025). ...
Diverse Proteomimetic Frameworks via Rational Design of π-Stacking Peptide Tectons.
Publié le 11/04/2025
... Ganatra, P., Wang, D.F., Ganatra, V., Dang, V.T., Nguyen, A.I. "Diverse Proteomimetic Frameworks via Rational Design of π-Stacking Peptide Tectons." Journal of the American Chemical Society., 146(32): 22236–22246. (2024). ...
Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.
Publié le 10/04/2025
... Shields, J.D., Aquila, B.M., Emmons, D., Finlay, M.R.V., Gangl, E.T., Gu, C., Mlynarski, S.N., Petersen, J., Pop-Damkov, P., Li Sha, L., Simpson, I., Tavakoli, S., Tentarelli, S., Wang, H., Ye, Q., Zheng, X.L. "Design and Synthesis of Acyclic Boronic Acid ...
NAL1 forms a molecular cage to regulate FZP phase separation
Publié le 10/04/2025
... Huang, L.Y., Wang, T.T., Shi, P.T., Song, Z.Y., Chen, W.F., Liu, N.N., Ai, X., Li, H.H., Hou, X.M., Wang, L.B., Chen, K.M., Rety, S., Xi, X.G. "NAL1 forms a molecular cage to regulate FZP phase separation" PNAS., 122(15): art.n° e2419961122. (2025). ...
Mechanism and kinetics of turnover inhibitors of nicotinamide N-methyl transferase in vitro and in vivo
Publié le 10/04/2025
... Akerud, T., De Fusco, C., Brandt, P., Bergström, F., Johansson, P., Ek, M., Börjesson, U., Johansson, A., Danielsson, J., Bauer, M., Arnaud, B., Castaldo, M., Strömstedt, M., Rosengren, B., Jansen, F., Fredlund, L. "Mechanism and kinetics of turnover ...
Que peut apporter SOLEIL à la communauté scientifique des biologistes - Rencontres scientifiques à Montpellier les 28 et 29 avril 2025
Publié le 09/04/2025
... Au programme de ces rencontres : des présentations croisées de scientifiques de Montpellier et des lignes de lumière de SOLEIL, organisées autour de deux thèmes principaux : l'imagerie et la biologie structurale. ...