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Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi
Publié le 17/04/2021
... Zhai, L.T., Chen, W.F., Song, Z.Y., Auguin, D., Sun, B., Dou, S.X., Xi, X.G. "Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi" Nucleic Acids Research., 49(8): 4768–4781. (2021). ...
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer’s Disease
Publié le 10/04/2021
... Rossi, M., Freschi, M., de Camargo Nascente, L., Salerno, A., de Melo Viana Teixeira, S., Nachon, F., Chantegreil, F., Soukup, O., Prchal, L., Malaguti, M., Bergamini, C., Bartolini, M., Angeloni, C., Hrelia, S., Soares Romeiro, L.A., Bolognesi, M.L. ...
Proteobacterial Origin of Protein Arginine Methylation and Regulation of Complex I Assembly by MidA
Publié le 09/04/2021
... Hameed, U.F.S., Sanislav, O., Lay,, S.T., Annesley, S.J., Jobichen, C., Fisher, P.R., Swaminathan, K., Arold, S.T. "Proteobacterial Origin of Protein Arginine Methylation and Regulation of Complex I Assembly by MidA" Cell Reports., 24(8): 1996-2004. ...
Structure and Dynamics of an Archeal Monoglyceride Lipase from Palaeococcus ferrophilus as Revealed by Crystallography and In Silico Analysis
Publié le 07/04/2021
... Labar, G., Brandt, N., Flaba, A., Wouters, J., Leherte, L. "Structure and Dynamics of an Archeal Monoglyceride Lipase from Palaeococcus ferrophilus as Revealed by Crystallography and In Silico Analysis" Biomolecules., 11(4): art.n° 533. (2021). ...
Lithocholic Acid-Based Design of Noncalcemic Vitamin D Receptor Agonists
Publié le 07/04/2021
... Gaikwad, S., González, M.C., Vilariño, D., Lasanta, G., Villaverde, C., Mouriño, A., Verlinden, L., Verstuyf, A., Peluso-Iltis, C., Rochel, N., Berkowska, K., Marcinkowska, E. "Lithocholic Acid-Based Design of Noncalcemic Vitamin D Receptor Agonists" ...
“Host in Host” Supramolecular Core‐Shell Type Systems Based on Giant Ring‐Shaped Polyoxometalate
Publié le 03/04/2021
... Falaise, C., Khlifi, S., Bauduin, P., Schmidt, P., Shepard, W., Ivanov, A.A., Sokolov, M.N., Abramov, P.A., Shestopalov, M.A., Cordier, S., Marrot, J., Haouas, M., Cadot, E. "“Host in Host” Supramolecular Core‐Shell Type Systems Based on Giant Ring‐Shaped ...
Discovery of multifunctional anti-Alzheimer’s agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters
Publié le 02/04/2021
... Pasieka, A., Panek, D., Jończyk,J., Godyń,J., Szałaj,N., Latacz,G., Tabor,J., Mezeiova,E., Chantegreil,F., Dias,J., Knez,D., Lu,J., Pi,R., Korabecny,J., Brazzolotto,X., Gobec,S., Höfner,G., Wanner,K., Więckowska,A., Malawska, B. "Discovery of ...
Physiological Metals Can Induce Conformational Changes in Transthyretin Structure: Neuroprotection or Misfolding Induction?
Publié le 02/04/2021
... Ciccone, L., Tonali, N., Shepard, W., Nencetti, S., Orlandini, E. "Physiological Metals Can Induce Conformational Changes in Transthyretin Structure: Neuroprotection or Misfolding Induction?" Crystals., 11(4): art.n° 354. (2021). ...
Synergy and allostery in ligand binding by HIV-1 Nef
Publié le 02/04/2021
... Aldehaiman, A.M., Momin, A.A., Restouin, A., Wang, L., Shi, X., Aljedani, S., Opi, S., Lugari, A., Hameed, U.F.S., Ponchon, L., Morelli, X., Huang, M., Dumas, C., Collette, Y., Arold, S. "Synergy and allostery in ligand binding by HIV-1 Nef" Biochemical ...
Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy
Publié le 10/03/2021
... Nissink, J.W.M., Bazzaz, S., Blackett, C., Clark, M.A., Collingwood, O., Disch, J.S., Gikunju, D., Goldberg, K., Guilinger, J.P., Hardaker, E., Hennessy, E.J., Jetson, R., Keefe, A.D., McCoull, W., McMurray, L., Olszewski, A., Overman, R., Pflug, A., ...