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Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling
Publié le 24/02/2017
... Adams, R., Burnley, R.J., Valenzano, C.R., Qureshi, O., Doyle, C., Lumb, S., Lopez, M.C., Griffin, R., McMillan, D., Taylor, R.D., Meier, C., Mori, P., Griffin, L.M., Wernery, U., Kinne, J., Rapecki, S., Baker, T.S., Lawson, A.D.G., Wright, M., Ettorre, A ...
Revisiting sulfur H-bonds in proteins: The example of peroxiredoxin AhpE
Publié le 22/02/2017
... Van Bergen, L.A.H., Alonso, M., Pallo, A., Nilsson, L., De Proft, F., Messens, J. "Revisiting sulfur H-bonds in proteins: The example of peroxiredoxin AhpE" Scientific Reports., 6: art.n° 30369 . (2016). ...
Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action
Publié le 22/02/2017
... Trajtenberg, F., Imelio, J.A., Machado, M.R., Larrieux, N., Marti, M.A., Obal, G., Mechaly, A.E., Buschiazzo, A. "Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action" eLife., 5: art.n° e21422. (2016). ...
TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL
Publié le 22/02/2017
... Thébault, S., Agez, M., Chi, X., Stojko, J., Cura, V., Telerman, S.B., Laurent Maillet, L., Gautier, F., Billas-Massobrio, I., Birck, C., Troffer-Charlier, N., Karafin, T., Honoré, J., Senff-Ribeiro, A., Montessuit, S., Johnson, C.M., Juin, P., Cianférani ...
Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS
Publié le 22/02/2017
... Talagas, A., Fontaine, L., Ledesma-Garca, L., Mignolet, J., Li de la Sierra-Gallay, I., Lazar, N., Aumont-Nicaise, M., Federle, M.J., Prehna, G., Hols, P., Nessler, S. "Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell ...
Highly selective inhibition of myosin motors provides the basis of potential therapeutic application
Publié le 22/02/2017
... Sirigu, S., Hartman, J.J., Planelles-Herrero, V.J., Ropars, V., Clancy, S., Wang, X., Chuang, G., Qian, X., Lu, P.P., Barrett, E., Rudolph, K., Royer, C., Morgan, B.P., Stura, E.A., Malik, F.I., Houdusse, A.M. "Highly selective inhibition of myosin motors ...
Discovery of phenoxyindazoles and phenylthioindazoles as RORγ inverse agonists
Publié le 22/02/2017
... Ouvry, G., Bouix-Peter, C., Ciesielski, F., Chantalat, L., Christin, O., Comino, C., Duvert, D., Feret, C., Harris, C.S., Lamy, L., Luzy, A.P., Musicki, B., Orfila, D., Pascau, J., Parnet, V., Perrin, A., Pierre, R., Polge, G., Raffin, C., Rival, Y., ...
Carborane-based design of a potent vitamin D receptor agonist
Publié le 22/02/2017
... Otero, R., Seoane, S., Sigüeiro, R., Belorusova, A.Y., Maestro, M.A., Pérez-Fernández, R., Rochel, N., Mouriño, A. "Carborane-based design of a potent vitamin D receptor agonist" Chemical Science., 7(2): 1033-1037. (2016). ...
Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3
Publié le 22/02/2017
... Mullapudi, E., Nováček,J., Pálková,L., Kulich,P., Lindberg,A.M., van Kuppeveld,F.J.M., Plevka, P. "Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3" Journal of Virology., 90(17): 7628-7639. (2016). ...
Molecular insights into protein synthesis with proline residuesMolecular insights into protein synthesis with proline residues
Publié le 22/02/2017
... Melnikov, S., Mailliot, J., Rigger, L., Neuner, S., Shin, B.S., Yusupova, G., Dever, T.E., Micura, R., Yusupov, M. "Molecular insights into protein synthesis with proline residuesMolecular insights into protein synthesis with proline residues" EMBO ...