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From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia
Publié le 31/05/2023
... Saez-Ayala, M., Hoffer, L., Abel, S., Ben Yaala, K., Sicard, B., Andrieu, G.P., Latiri, M., Davison, E.K., Ciufolini, M.A., Brémond, P., Rebuffet, E., Roche, P., Derviaux, C., Voisset, E., Montersino, C., Castellano, R., Collette, Y., Asnafi, V., Betzi, S ...
Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity
Publié le 17/05/2023
... Genera, M., Colcombet-Cazenave, B., Croitoru, A., Raynal, B., Mechaly, A., Caillet, J., Haouz, A., Wolff, N., Caillet-Saguy, C. "Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into ...
Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system
Publié le 16/05/2023
... Blanc, M., Lettl, C., Guérin, J., Vieille, A., Furler, S., Briand-Schumacher, S., Dreier, B., Bergé, C., Plückthun, A., Vadon-Le Goff, S., Fronzes, R., Rousselle, P., Fischer, W., Terradot, L. "Designed Ankyrin Repeat Proteins provide insights into the ...
DNA-binding mechanism and evolution of replication protein A
Publié le 24/04/2023
... Madru, C., Martínez-Carranza, M., Laurent, S., Alberti, A.C., Chevreuil, M., Raynal, B., Haouz, A., Le Meur, R.A., Delarue, M., Henneke, G., Flament, D., Krupovic, M., Legrand, P., Sauguet, L. "DNA-binding mechanism and evolution of replication protein A" ...
Biochemical characterization of a GDP-mannose transporter from Chaetomium thermophilum
Publié le 21/04/2023
... Premageetha, G.T.R., Dhanabalan, K.V., Bose, S., Manjunath, L., Joseph, D., Paz, A., Grandfield, S., Nayak, V., Bredeston, L.M., Abramson, J., Ramaswamy, S. "Biochemical characterization of a GDP-mannose transporter from Chaetomium thermophilum" PLoS One. ...
Reclassification of family A DNA polymerases reveals novel functional subfamilies and distinctive structural features
Publié le 20/04/2023
... Czernecki, D., Nourisson, A., Legrand, P., Delarue, M. "Reclassification of family A DNA polymerases reveals novel functional subfamilies and distinctive structural features" Nucleic Acids Research., 51(9): 4488–4507. (2023). ...
The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis
Publié le 03/04/2023
... Bimai, O., Legrand, P., Ravanat, J.L., Touati, N., Zhou, J., He, N., Lénon, M., Barras, F., Fontecave, M., Golinelli-Pimpaneau, B. "The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum ...
Biochemical and structural analysis of N-myristoyltransferase mediated protein tagging
Publié le 29/03/2023
... Monassa, P., Rivière, F., Dian, C., Frottin, F., Giglione, C., Meinnel, T. "Biochemical and structural analysis of N-myristoyltransferase mediated protein tagging" Methods in Enzymology., 684: 135-166. (2023). ...
Characterization of human oxidoreductases involved in aldehyde odorant metabolism
Publié le 27/03/2023
... Boichot, V., Menetrier, F., Saliou, J.M., Lirussi, F., Canon, F., Folia, M., Heydel, J.M., Hummel, T., Menzel, S., Steinke, M., Hackenberg, S., Schwartz, M., Neiers , F. "Characterization of human oxidoreductases involved in aldehyde odorant metabolism" ...
Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors
Publié le 22/03/2023
... Krammer, E.M., Bridot, C., Serna, S., Echeverria, B., Semwal, S., Roubinet, B., van Noort, K., Wilbers, R.H.P., Bourenkov,G., de Ruyck, J., Landemarre, L., Reichardt, N., Bouckaert, J. "Structural insights into a cooperative switch between one and two ...