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Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus
Publié le 13/03/2025
... Ewert, W., Bartens, C., Ongouta, J., Holmes, M., Heutling, A., Kishore, A., Urbansky, T., Zeilinger, C., Preller, M., Kirschning, A. "Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus" Nature Communications., 16: ...
Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel
Publié le 13/03/2025
... Karlsson, E., Andén, O., Fan, C., Fourati, Z., Haouz, A., Zhuang, Y., Howard, R.J., Delarue, M., Lindahl, E. "Vestibular modulation by stimulant derivatives in a pentameric ligand-gated ion channel" British Journal of Pharmacology., 182(12): 2790-2802. ...
Structure, function and catalytic mechanism of the carrageenan-sulfatases from the marine bacterium Zobellia galactanivorans DsijT
Publié le 11/03/2025
... Chevenier, A., Fanuel, M., Sokolova, E., Latorre, D.M., Jouanneau, D., Jeudy, A., Préchoux, A., Zühlke, M.K., Bartel, J., Becher, D., Czjzek, M., Ropartz, D., Michel, G., Ficko-Blean, E. "Structure, function and catalytic mechanism of the carrageenan ...
Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State
Publié le 25/02/2025
... Pecqueur, L., Lombard, M., Hamdane, D. "Structural Plasticity of Flavin-Dependent Thymidylate Synthase Controlled by the Enzyme Redox State" Biomolecules., 15(3): art.n° 318. (2025). ...
Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms
Publié le 22/02/2025
... Rivière, F., Dian, C., Dutheil, R.F., Monassa, P., Giglione, C., Meinnel, T. "Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms" Structure., 32(10): 1737-1750. (2024). ...
N-Terminal Protein Binding and Disorder-to-Order Transition by a Synthetic Receptor
Publié le 22/02/2025
... Mockler, N.M., Ramberg, K.O., Flood, R.J., Crowley, P.B. "N-Terminal Protein Binding and Disorder-to-Order Transition by a Synthetic Receptor" Biochemistry., 64(5): 1092–1098. (2025). ...
ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
Publié le 22/02/2025
... Mishra, S., Malhotra, N., Laleu, B., Chakraborti, S., Yogavel, M., Sharma, A. "ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development" iScience., 27(7): art.n° 110049. (2024). ...
Structural insights into tecovirimat antiviral activity and poxvirus resistance
Publié le 14/02/2025
... Vernuccio, R., Martínez León, A., Poojari, C.S., Buchrieser, J., Selverian, C.N., Jaleta, Y., Meola, A., Guivel-Benhassine, F., Porrot, F., Haouz, A., Chevreuil, M., Raynal, B., Mercer, J., Simon-Loriere, S., Chandran, K., Schwartz, O., Hub, J.S., ...
Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair
Publié le 11/02/2025
... Claustre, A., Malige, M., Macheton, M., Combaret, L., Lefai, E., Fafournoux, P., Taillandier, D., Henri, J., Polge, C. "Structure predictions of MuRF1-UBE2 complexes identify amino acid residues governing interaction selectivity for each MuRF1-E2 pair" ...
Otitiglycomycins A and B: Glycolipids from the Strain Nocardia otitidiscavarum 20S-13 with Antiviral Activity against Zika Virus
Publié le 05/02/2025
... Mai, P.Y., Marguerite, E., Ouazzani, J., Lopes, P., Retailleau, P., Gallard, J.F., Moppert, X., Costa, B., Le Goff, G., El Kalamouni, C., Poupon, E., Beniddir, M.A. "Otitiglycomycins A and B: Glycolipids from the Strain Nocardia otitidiscavarum 20S-13 ...