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N-Acylbenzimidazoles as Selective Acylators of the Catalytic Cystein of the Coronavirus 3CL Protease
Publié le 26/07/2024
... Chaibi, F.Z., Brier, L., Carré, P., Landry, V., Desmarets, L., Tarricone, A., Cantrelle, F.X., Moschidi, D., Herledan, A., Biela, A., Bourgeois, F., Ribes, C., Ikherbane, S., Malessan, M., Dubuisson, J., Belouzard, S., Hanoulle, X., Leroux,, Deprez, B., ...
Constrained Catalytic Itinerary of a Retaining 3,6-Anhydro-D-Galactosidase, a Key Enzyme in Red Algal Cell Wall Degradation
Publié le 19/07/2024
... Wallace, M.D., Cuxart, I., Roret, T., Guée, L., Debowski, A.W., Czjzek, M., Rovira, C., Stubbs, K.A., Ficko-Blean, E. "Constrained Catalytic Itinerary of a Retaining 3,6-Anhydro-D-Galactosidase, a Key Enzyme in Red Algal Cell Wall Degradation" Angewandte ...
Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution
Publié le 16/07/2024
... Ghiglione, B., Rodríguez, M.M., Penzotti, P., Bethel, C.R., Gutkind, G., Bonomo, R.A., Klinke, S., Power, P. "Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution" Antimicrobial ...
A vitamin D-based strategy overcomes chemoresistance in prostate cancer
Publié le 11/07/2024
... Len-Tayon, K., Beraud, C., Fauveau, C., Belorusova, A.Y., Chebaro, Y., Mouriño, A., Massfelder, T., Chauchereau, A., Metzger, D., Rochel, N., Laverny, G. "A vitamin D-based strategy overcomes chemoresistance in prostate cancer" British Journal of ...
Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus
Publié le 05/07/2024
... Fernández, I., Saunders, N., Duquerroy, S., Bolland, W.H., Arbabian, A., Baquero, E., Blanc, C., Lafaye, P., Haouz, A., Buchrieser, J., Schwartz, O., Rey, F.A. "Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal ...
Structural and Thermodynamic Insights into Dimerization In-Terfaces of Drosophila Glutathione Transferases
Publié le 27/06/2024
... Schwartz, M., Petiot, N., Chaloyard, J., Senty-Segault, V., Lirussi, F., Senet, P., Nicolai, A., Heydel, J.M., Canon, F., Sonkaria, S., Khare, V., Didierjean, C., Neiers, F. "Structural and Thermodynamic Insights into Dimerization In-Terfaces of ...
Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain
Publié le 11/06/2024
... Gómez-Bouzó, U., Peluso-Iltis, C., Santalla, H., Quevedo, M.A., Verlinden, L., Verstuyf, A., Fall, Y., Gómez, G., Rochel, N. "Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain" ...
Optimization of Cr/Sc-based multilayer mirrors for water window soft x-rays
Publié le 10/06/2024
... Meltchakov, E., Capitanio, B., de Rossi, S., Papagiannouli, I., Mercère, P., Delmotte, F. "Optimization of Cr/Sc-based multilayer mirrors for water window soft x-rays" Optics Letters., 49(12): 3420-3423. (2024). ...
Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction
Publié le 10/06/2024
... Auguin, D., Robert-Paganin, J., Réty, S., Kikuti, C., David, A., Theumer, G., Schmidt, A.W., Knölker, H.J., Houdusse, A. "Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction" Nature Communications. ...
Mechanisms of neutralization of toxSAS from toxin–antitoxin modules
Publié le 06/06/2024
... Dominguez-Molina, L., Kurata, T., Cepauskas, A., Echemendia-Blanco, D., Zedek, S., Talavera-Perez, A., Atkinson, G.C., Hauryliuk, V., Garcia-Pino, A. "Mechanisms of neutralization of toxSAS from toxin–antitoxin modules" Nature Chemical Biology., 21(2): ...