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Résultats de la recherche ""
Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies
Publié le 28/11/2024
... Cecil, A.J., Sogues, A., Gurumurthi, M., Lane, K.S., Remaut, H., Pak, A.J. "Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies" PNAS Nexus., 3(12): art.n° pgae538. (2024). ...
Dimerization of ADAR1 modulates site-specificity of RNA editing
Publié le 22/11/2024
... Mboukou, A., Rajendra, V., Messmer, S., Mandl, T.C., Catala, M., Tisné, C., Jantsch, M.F., Barraud, P. "Dimerization of ADAR1 modulates site-specificity of RNA editing" Nature Communications., 15: art.n° 10051. (2024). ...
Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands
Publié le 05/11/2024
... Antonini, G., Bernardi, A., Gillon, E., Dal Corso, A., Civera, M., Belvisi, L., Varrot, A., Mazzotta, S. "Achieving High Affinity for a Bacterial Lectin with Reversible Covalent Ligands" Journal of Medicinal Chemistry., 67(21): 19546-19560. (2024). ...
The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau mechanism and oligomerization
Publié le 31/10/2024
... Ammar Khodja, L., Campanacci, V., Lippens, G., Gigant, B. "The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau mechanism and oligomerization" PNAS Nexus., 3(11): art.n° 487. (2024). ...
RNase W, a conserved ribonuclease family with a novel active site
Publié le 29/10/2024
... Vayssières, M., Jüttner, M., Haas, K., Ancelin, A., Marchfelder, A., Leulliot, N., Ferreira-Cerca, S., Blaud, M. "RNase W, a conserved ribonuclease family with a novel active site" Nucleic Acids Research., 52(21): 13386–13401. (2024). ...
Experimental Characterization of the Isomer-Selective Generation of the Astrochemically Relevant Hydroxymethylene Radical Cation (HCOH•+/DCOH•+)
Publié le 26/10/2024
... Richardson, V., Alcock, L., Solem, N., Sundelin, D., Romanzin, C., Thissen, R., Geppert, W.D., Alcaraz, C., Polášek, M., Heazlewood, B.R., Autret, Q., Ascenzi, D. "Experimental Characterization of the Isomer-Selective Generation of the Astrochemically ...
Pyrrolizwilline, a unique bacterial alkaloid assembled by a nonribosomal peptide synthetase and non-enzymatic dimerization
Publié le 21/10/2024
... Effert, J., Westphalen, M., Calderari, A., Shi, Y.M., Elamri, I., Najah, S., Grün, P., Li, Y., Gruez, A., Weissman, K.J., Bode, H.B. "Pyrrolizwilline, a unique bacterial alkaloid assembled by a nonribosomal peptide synthetase and non-enzymatic ...
Rational fragment-based design of compounds targeting the PWWP domain of the HRP family
Publié le 11/10/2024
... Vantieghem, T., Aslam, N.A., Osipov, E.M., Akele, M., Van Belle, S., Beelen, S., Drexler, M., Paulovcakova, T., Lux, V., Fearon, D., Douangamath, A., von Delft, F., Christ, F., Veverka, V., Verwilst, P., Van Aerschot, A., Debyser, Z., Strelkov, S.V. ...
Drug-resistant menin variants retain high binding affinity and interactions with MLL1
Publié le 11/10/2024
... Ray, J., Clegg, B., Grembecka, J., Cierpicki, T. "Drug-resistant menin variants retain high binding affinity and interactions with MLL1" Journal of Biological Chemistry., 300(10): art.n° 107777. (2024). ...
Bifunctional Hexadentate Pyclen-based Chelating Agent for Mild Radiofluorination in Aqueous Solution at Room Temperature with a Ga-18F Ternary Complex
Publié le 01/10/2024
... Dioury, F., San, C., Gnanalingam, G., Henoumont, C., Haouz, A., Shepard, W., Rousselin, Y., Vijayakumar, K., Hosten, B., Laurent, S., Port, M. "Bifunctional Hexadentate Pyclen-based Chelating Agent for Mild Radiofluorination in Aqueous Solution at Room ...