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Polyoxometalate-Directed Assembly of Robust Coordination Cages: Overcoming Kinetic Inertness and Conformational Mismatch
Publié le 13/10/2025
... Liu, C.L., Jia, X., Ham, R., Ren, C., Van Meervelt, L., Reek, J.N.H., Parac-Vogt, T.N. "Polyoxometalate-Directed Assembly of Robust Coordination Cages: Overcoming Kinetic Inertness and Conformational Mismatch" Angewandte Chemie International Edition., 64 ...
Dipeptidase 1 is a functional receptor for a porcine coronavirus
Publié le 13/10/2025
... Dufloo, J., Fernández, I., Arbabian, A., Haouz, A., Temperton, N., Gimenez-Lirola, L.G., Rey, F.A., Sanjuán, R. "Dipeptidase 1 is a functional receptor for a porcine coronavirus" Nature Microbiology., 10(11): 2981–2996. (2025). ...
Une nouvelle cible pour traiter le virus mpox (variole du singe) et d’autres infections poxvirales
Publié le 10/09/2025
... Le mpox est une maladie infectieuse transmise par contact, pouvant être mortelle ou laisser des séquelles importantes. Des chercheurs de l’Institut Pasteur ont identifié et caractérisé une nouvelle cible pour développer des thérapies capables ...
Reconstruction kinetics and structural evolutions of chromate and chloride intercalated Mg/Al layered double hydroxide in low-carbon cements
Publié le 21/08/2025
... Zhang, Y., Zhu, X., Ma, B., Li, X., Xu, W., Wang, L., Maboudian, R., Tsang, D.C.W. "Reconstruction kinetics and structural evolutions of chromate and chloride intercalated Mg/Al layered double hydroxide in low-carbon cements" Cement and Concrete ...
Fidelity, specialization, and evolution of Paramecium PolX DNA polymerases involved in programmed double-strand break DNA repair
Publié le 20/08/2025
... Nourisson, A., Missoury, S., Lucas-Staat, S., Haouz, A., Delarue, M. "Fidelity, specialization, and evolution of Paramecium PolX DNA polymerases involved in programmed double-strand break DNA repair" Nucleic Acids Research., 53(15): art.n° gkaf786. (2025 ...
Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases
Publié le 19/08/2025
... Hoff, J.F., Goudar, K.E., Calvopiña, K., Beer, M., Hinchliffe, P., Shaw, J., Tooke, C.L., Takebayashi, Y., Cadzow, A., Harmer, N., Mulholland, A.J., Schofield, C.J., Spencer, J. "Electrostatic interactions influence diazabicyclooctane inhibitor potency ...
Cryo-EM identifies F-ENA of Bacillus thuringiensis as a widespread family of endospore appendages across Firmicutes
Publié le 19/08/2025
... Sleutel, M., Sogues, A., Van Gerven, N., Jonsmoen, U.L., Van Molle, I., Marcus Fislage, M., Theunissen, L.D., Bellis, N.F., Baquero, D.P., Egelman, E.H., Krupovic, M., Wang, F., Aspholm, M., Remaut, H. "Cryo-EM identifies F-ENA of Bacillus thuringiensis ...
Structural and Enzymological Characterization of Phosphoserine Phosphatase From Brucella melitensis
Publié le 13/08/2025
... Scaillet, T., Pierson, E., Fillet, M., Wouters, J. "Structural and Enzymological Characterization of Phosphoserine Phosphatase From Brucella melitensis" Proteins Structure Function and Bioinformatics., 94(2): 502-514. (2026). ...
The adaptability of the fungal tRNA ligase's ATP-binding pocket: a potential target for new antifungal drugs
Publié le 13/08/2025
... McEwen, A.G., Giovinazzo, A., Poussin-Courmontagne, P., Merolle, M., Tocchini-Valentini, G.P., Pellegrini, M., Tocchini-Valentini, G.D. "The adaptability of the fungal tRNA ligase's ATP-binding pocket: a potential target for new antifungal drugs" NAR ...
Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target
Publié le 13/08/2025
... Ketprasit, N., Tai, C.W., Sharma, V.K., Manickam, Y., Khandokar, Y., Ye, X., Dogovski, C., Hilko,D.H., Morton, C.J., Braun, A.S.C., Leeming, M.G., Siddharam, B., Shami, G.J., Pradeepkumar, P.I., Panjikar, S., Poulsen, S.A., Griffin, M.D.W., Sharma, A., ...