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Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases
Publié le 19/08/2025
... Hoff, J.F., Goudar, K.E., Calvopiña, K., Beer, M., Hinchliffe, P., Shaw, J., Tooke, C.L., Takebayashi, Y., Cadzow, A., Harmer, N., Mulholland, A.J., Schofield, C.J., Spencer, J. "Electrostatic interactions influence diazabicyclooctane inhibitor potency ...
Cryo-EM identifies F-ENA of Bacillus thuringiensis as a widespread family of endospore appendages across Firmicutes
Publié le 19/08/2025
... Sleutel, M., Sogues, A., Van Gerven, N., Jonsmoen, U.L., Van Molle, I., Marcus Fislage, M., Theunissen, L.D., Bellis, N.F., Baquero, D.P., Egelman, E.H., Krupovic, M., Wang, F., Aspholm, M., Remaut, H. "Cryo-EM identifies F-ENA of Bacillus thuringiensis ...
Structural and Enzymological Characterization of Phosphoserine Phosphatase From Brucella melitensis
Publié le 13/08/2025
... Scaillet, T., Pierson, E., Fillet, M., Wouters, J. "Structural and Enzymological Characterization of Phosphoserine Phosphatase From Brucella melitensis" Proteins Structure Function and Bioinformatics., 94(2): 502-514. (2026). ...
The adaptability of the fungal tRNA ligase's ATP-binding pocket: a potential target for new antifungal drugs
Publié le 13/08/2025
... McEwen, A.G., Giovinazzo, A., Poussin-Courmontagne, P., Merolle, M., Tocchini-Valentini, G.P., Pellegrini, M., Tocchini-Valentini, G.D. "The adaptability of the fungal tRNA ligase's ATP-binding pocket: a potential target for new antifungal drugs" NAR ...
Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target
Publié le 13/08/2025
... Ketprasit, N., Tai, C.W., Sharma, V.K., Manickam, Y., Khandokar, Y., Ye, X., Dogovski, C., Hilko,D.H., Morton, C.J., Braun, A.S.C., Leeming, M.G., Siddharam, B., Shami, G.J., Pradeepkumar, P.I., Panjikar, S., Poulsen, S.A., Griffin, M.D.W., Sharma, A., ...
Structural variations of transketolases over the evolution from bacteria to higher eukaryotes: In silico/in vitro study
Publié le 13/08/2025
... Georges, R.N., Ballut, L., Charmantray, F., Doumèche, B. "Structural variations of transketolases over the evolution from bacteria to higher eukaryotes: In silico/in vitro study" Methods in Enzymology., 722: 247-282. (2025). ...
Ancestral [Fe-S] biogenesis system SMS has a unique mechanism of cluster assembly and sulfur utilization
Publié le 13/08/2025
... Dussouchaud, M., Martinez-Carranza, M., Garcia, P.S., Clémancey, M., Blondin, G., Betton, J.M., Haouz, A., Gribaldo, S., Ollagnier de Choudens, S., Sauguet, L., Mechaly, A., Barras, F. "Ancestral [Fe-S] biogenesis system SMS has a unique mechanism of ...
Crystal engineering of the hepatoma-derived growth factor-related protein 2 PWWP domain towards crystallographic fragment screening
Publié le 05/08/2025
... Vantieghem, T., Osipov, E. M., Beelen, S., Strelkov, S. V. "Crystal engineering of the hepatoma-derived growth factor-related protein 2 PWWP domain towards crystallographic fragment screening" Acta Crystallographica F., 81(8): 358-364. (2025). ...
Protein Recognition and Assembly by a Phosphocavitand
Publié le 29/07/2025
... Wren, C. P., Flood, R. J., Mockler, N. M., Savko, M., Malinska, M., Shi, Q., Crowley, P. B. "Protein Recognition and Assembly by a Phosphocavitand" Journal of the American Chemical Society., 147(31): 28107–28116. (2025). ...
Electric Field Distribution within a Van der Waals Heterostructure
Publié le 16/07/2025
... Mastrippolito, D., Cavallo, M., Bossavit, E., Gureghian, C., Colle, A., Gemo, T., Strobbia, G., De Pesseroey, D., Paye, M., Khalili, A., Zhang, H., Biscaras, J., Utterback, J. K., Dudin, P., Avila, J., Lhuillier, E., Pierucci, D. "Electric Field ...