Dernière mise à jour : 05/11/2025
Li, C., Moro, S., Shostak, K., O’Reilly, F.J., Donzeau, M., Graziadei, A., McEwen, A.G., Desplancq, D., Poussin-Courmontagne, P., Bachelart, T., Fiskin, M., Berrodier, N., Pichard, S., Brillet, K., Orfanoudakis, G., Poterszman, A., Torbeev, V., Rappsilber, J., Davey, N.E., Chariot, A., Zanier, K. "Molecular mechanism of IKK catalytic dimer docking to NF-κB substrates" Nature Communications., 15: art.n° 7692. (2024).
Stockwell, S.R., Scott, D.E., Fischer, G., Guarino, E., Rooney, T.P.C., Feng, T.S., Moschetti, T., Srinivasan, R., Alza, E., Asteian, A., Dagostin, C., Alcaide, A., Rocaboy, M., Blaszczyk, B., Higueruelo, A., Wang, X., Rossmann, M., Perrior, T.R., Blundell, T.L., Spring, D.R., McKenzie, G., Abell, C., Skidmore, J., Venkitaraman, A.R., Hyvönen, M. "Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents" Journal of Medicinal Chemistry., 67(17): 15521-15536. (2024).
Fernández, I., Saunders, N., Duquerroy, S., Bolland, W.H., Arbabian, A., Baquero, E., Blanc, C., Lafaye, P., Haouz, A., Buchrieser, J., Schwartz, O., Rey, F.A. "Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus" Cell., 187(16): 4246-4260. (2024).
Ghiglione, B., Rodríguez, M.M., Penzotti, P., Bethel, C.R., Gutkind, G., Bonomo, R.A., Klinke, S., Power, P. "Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution" Antimicrobial Agents and Chemotherapy., 68(8): art.n° 1721-23. (2024).
Ganatra, P., Wang, D.F., Ganatra, V., Dang, V.T., Nguyen, A.I. "Diverse Proteomimetic Frameworks via Rational Design of π-Stacking Peptide Tectons." Journal of the American Chemical Society., 146(32): 22236–22246. (2024).
Chaibi, F.Z., Brier, L., Carré, P., Landry, V., Desmarets, L., Tarricone, A., Cantrelle, F.X., Moschidi, D., Herledan, A., Biela, A., Bourgeois, F., Ribes, C., Ikherbane, S., Malessan, M., Dubuisson, J., Belouzard, S., Hanoulle, X., Leroux,, Deprez, B., Charton, J. "N-Acylbenzimidazoles as Selective Acylators of the Catalytic Cystein of the Coronavirus 3CL Protease" European Journal of Medicinal Chemistry., 276: art.n° 116707. (2024).
Mishra, S., Malhotra, N., Laleu, B., Chakraborti, S., Yogavel, M., Sharma, A. "ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development" iScience., 27(7): art.n° 110049. (2024).
Gómez-Bouzó, U., Peluso-Iltis, C., Santalla, H., Quevedo, M.A., Verlinden, L., Verstuyf, A., Fall, Y., Gómez, G., Rochel, N. "Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain" Journal of Medicinal Chemistry., 67(12): 10386–10400. (2024).
Schwartz, M., Petiot, N., Chaloyard, J., Senty-Segault, V., Lirussi, F., Senet, P., Nicolai, A., Heydel, J.M., Canon, F., Sonkaria, S., Khare, V., Didierjean, C., Neiers, F. "Structural and Thermodynamic Insights into Dimerization In-Terfaces of Drosophila Glutathione Transferases" Biomolecules., 14(7): art.n° 758. (2024).
Auguin, D., Robert-Paganin, J., Réty, S., Kikuti, C., David, A., Theumer, G., Schmidt, A.W., Knölker, H.J., Houdusse, A. "Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction" Nature Communications., 15: art.n° 4885. (2024).