Dernière mise à jour : 01/11/2025
Mourot, L., Chaibi, F.Z., Bou-Karroum, N., Carré, P., Abengozar Munoz, A., Landry, V., Tarricone, A., Biela, A., Piveteau, C., Novikov, G., Dupré, E., Dubuisson, J., Belouzard, S., Leroux, F., Deprez, B., Hanoulle, X., Charton, J. "A new chemotype that opens the S2* pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2." European Journal of Medicinal Chemistry., 302(1): art.n° 118277. (2026).
Meola, A., Vernuccio, R., Battini, L., Albericio, G., Delgado, P., Bamford, R., Pokorny, L., Broutin, M., Martínez León, A., Gallien, S., Gil, M., Noriega, M.A., Guivel-Benhassine, F., Porrot, F., Postal, J., Buchrieser, J., Hubert, M., Haouz, A., Lafaye, P., Esteban, M., Guardado-Calvo, P. "Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection" Cell., 188(22): 6266-6282. (2025).
Aragao, D., Savko, M., Oram, D., Smith, K., Shepard, W., Flaig, R. "Accelerating Synchrotron MX Beamlines: Automated Sample Centering with Machine Learning and Bluesky Orchestration" Structural Dynamics., 12(5): art.n° A47. (2025).
Huntington, B., Sandholu, A., Wang, J., Zhang, J., Zhao, L., Qureshi, B., Hameed, U.F.S., Arold, S.T. "Cryo-EM structural analyses reveal plant-specific adaptations of the CDC48 unfoldase". Plant Communications., on line first (27/10/2025): (2025).
Dufloo, J., Fernández, I., Arbabian, A., Haouz, A., Temperton, N., Gimenez-Lirola, L.G., Rey, F.A., Sanjuán, R. "Dipeptidase 1 is a functional receptor for a porcine coronavirus". Nature Microbiology., on line first (13/10/2025): (2025).
Liu, C.L., Jia, X., Ham, R., Ren, C., Van Meervelt, L., Reek, J.N.H., Parac-Vogt, T.N. "Polyoxometalate-Directed Assembly of Robust Coordination Cages: Overcoming Kinetic Inertness and Conformational Mismatch". Angewandte Chemie International Edition., on line first (13/10/2025): (2025).
Sarmadi, F., Caza, A., Gao, Z., Rochel, N., Gleason, J.L., White, J.H. "Hyperagonism of a Vitamin D Receptor Agonist/Histone Deacetylase Inhibitor Hybrid Molecule" Journal of Medicinal Chemistry., 68(19): 20675-20688. (2025).
Mann, S.E., Lefranc, J., Alkhatib, O., Boivin, R., Bomke, J., Byrne, R.T., Cassona, C.P., Chen, X., Cornaciu, I., Costales, P., Davis, O.A., DeSelm, L., Elinati, E., Follows, B., Galbiati, A., Goldner, C., Hayre, J.K., Jorand-Lebrun, C., Lademann, C.A., Leuthner, B., Majithiya, J.B., Malta, C.F., Mason, B., McWhirter, C.L., Neff, B., Nissink, J.W.M., Pehl, U., Petersson, C., Pica, A., Pinto, M.F., Rajendra, E., Rakers, C., Toste Rego, A., Robinson, H.M.R., Sala-Hojman, A., Schaedler, T.A., Schurmann, P.J.L., Silva, D.O., Smith, G.C.M., Sorrell, F., Webster, G.R., Zenke, F.T., Heald, R.A., Burgdorf, L.T. "Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor" Journal of Medicinal Chemistry., 68(19): 20410–20434. (2025).
Ferchaud, N., Kopečný, D., Peřina,M., Boyer, A., Hentati, S., Pontoizeau, C., Desterke, C., Kryštof,V., Machover,D., Briozzo, P. "The methioninase from the alkalithermophile Thermobrachium celere possesses suitable properties for treatment of cancer" International Journal of Biological Macromolecules., 330(2): art.n° 147876. (2025).
Froes, T.Q., Alegbejo Price, T.O., Fleck Godoi, B., Vaidergorn, M.M., Dos Santos, T., Leite, P.I.P., Silva, D.G., Dias da Purificação, A., Loch, L., Schenkman, S., Kratz, J.M., da Silva Emery, F., Nonato, M.C. "Barbituric Acid Derivatives as Covalent Inhibitors of Leishmania braziliensis Dihydroorotate Dehydrogenase" Journal of Medicinal Chemistry., 68(18): 18869–18884. (2025).