Dernière mise à jour : 06/05/2025
Gu, W., Martinez, S., Singh, A.K., Nguyen, H., Rozenski, J., Schols, D., Herdewijn, P., Das, K., De Jonghe, S. "Exploring the dNTP -binding site of HIV-1 reverse transcriptase for inhibitor design" European Journal of Medicinal Chemistry., 225: art.n° 113785. (2021).
Song, L., Merceron, R., Hulpia, F., Lucía, A., Gracia, B., Jian, Y., Risseeuw, M.D.P., Verstraelen, T., Cos, P., Aínsa, J.A., Boshoff, H.I.M., Munier-Lehmann, H., Savvides, S.N., Van Calenbergh, S. "Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors" European Journal of Medicinal Chemistry., 225: art.n° 113784. (2021).
Muller, M.C., Wagner, T. "The Oxoglutarate Binding Site and Regulatory Mechanism Are Conserved in Ammonium Transporter Inhibitors GlnKs from Methanococcales" International Journal of Molecular Sciences., 22(16): art.n° 8631. (2021).
Martínez-Alarcón, D., Balloy, V., Bouchara, J.P., Pieters, R.J., Varrot, A. "Biochemical and structural studies of target lectin SapL1 from the emerging opportunistic microfungus Scedosporium apiospermum" Scientific Reports., 11: art.n° 16109. (2021).
Czernecki, D., Bonhomme, F., Kaminski, P.A., Delarue, M. "Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA" Nature Communications., 12: art.n° 4710. (2021).
González, C.M., Gaikwad, S., Lasanta, G., Loureiro, J., Nilsson, N., Peluso-Iltis, C., Rochel, N., Mouriño, A. "Design, Synthesis and Evaluation of Side-Chain Hydroxylated Derivatives of Lithocholic Acid as Potent Agonists of the Vitamin D Receptor (VDR)" Bioorganic Chemistry., 115: art.n° 105202. (2021).
Ghouil, R., Miron, S., Koornneef, L., Veerman, J., Paul, M.W., Le Du, M.H., Sleddens-Linkels, E., van Rossum-Fikkert, S.E., van Loon, Y., Felipe-Medina, N., Pendas, A.M., Maas, A., Essers, J., Legrand, P., Baarends, W.M., Kanaar, R., Zinn-Justin, S., Zelensky, A.N. "BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination" Nature Communications., 12: art.n° 4605. (2021).
Cerutti, G., Gugole, E., Montemiglio, L.C., Turbé-Doan, A., Chena, D., Navarro, D., Lomascolo, A., Piumi, F., Exertier, C., Freda, I., Vallone, B., Record, E., Savino, C., Sciara, G. "Crystal structure and functional characterization of an oligosaccharide dehydrogenase from Pycnoporus cinnabarinus provides insights into fungal breakdown of lignocellulose" Biotechnology for Biofuels., 14: art.n° 161. (2021).
Cowell, A.R., Jacquemet, G., Singh, A.K., Varela, L, Nylund, A.S., Ammon, Y.C., Brown, D.G., Akhmanova, A., Ivaska, J., Goult, B.T. "Talin rod domain–containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation" Journal of Cell Biology., 220(9): art.n° e202005214. (2021).
Lal, K., Bermeo, R., Cramer, J., Vasile, F., Ernst, B., Bernardi, A., Belvisi, L., Varrot, A., Imberty, A. "Prediction and Validation of a Druggable Site on Virulence Factor of Drug Resistant Burkholderia cenocepacia" Chemistry - A European Journal., 27(40): 10341-10348. (2021).