DESIRS beamline
ASSOCIATED PUBLICATION
Nanosolvation-induced stabilization
of a protonated peptide dimer isolated
in the gas phase
A. R. Milosavljevi
ć
*, V. Z. Cerovski, F. Canon,
L. Nahon and A. Giuliani
Angewandte Chemie International Edition
52(28) (2013) 7286
* Institute of Physics, University of Belgrade,
Pregrevica 118, 11080 Belgrade, Serbia
CORRESPONDING AUTHOR
➊
Principle of the experimental method.
➌
B3LYP/6-31+G(d,p) optimized geometry
of the lowest energy CF1 conformer found
of [2 Leu-Enk+3H
2
O+H]
+
and the corresponding
bare dimer CF1’ [2 Leu-Enk+H]
+
. Thin gray lines
represent H-bonds; black lines denote NH
3
group
➋
Nanosolvation of a leucine–
enkephalin peptide dimer by only
3 water molecules has a dramatic
impact on its stability to VUV photon
irradiation. A significant reduction
of the fragmentation abundance
of the hydrated protonated peptide
dimer precursor, isolated in the
gas phase, was observed. Bottom:
photoionization yields of [2Leu-
Enk+3H
2
O+H]
2+
(m/z 582.25–584.0)
fragment. The full line represents
the linear Wannier fit.
REFERENCE
[1] A.R. Milosavljevi
ć
et al. Journal
of synchrotron radiation 19 (2012), 174
87
SOLEIL
HIGHLIGHTS
2013
