CRISTAL beamline
ASSOCIATED PUBLICATION
Rationale of drug encapsulation and release
from biocompatible porous Metal−Organic
Frameworks
D. Cunha, M. Ben Yahia, S. Hall, S. R. Miller,
H. Chevreau, E. Elkaïm, G. Maurin,
P. Horcajada*, and C. Serre
Chemistry of Materials 25 (2013) 2767
*Institut Lavoisier, UMR CNRS 8180, Université
de Versailles Saint-Quentin-en-Yvelines, 45
avenue des Etats-Unis, 78035 Versailles cedex,
France
CORRESPONDING AUTHOR
➊
Schematic representation of the selected MOFs : MIL-100(Fe), MIL-127(Fe), MIL-53(Fe) and UiO-66(Zr)
structures and caffeine molecule (MIL: Materials from Institut Lavoisier; UiO: University of Oslo). Iron and
zirconium polyhedra and carbon atoms are in orange, blue and black, respectively. Hydrogen atoms have
been omitted for clarity.
➋
Caffeine release from UiO-66(Zr) and MIL-100(Fe) under simulated serum (left) or skin conditions
(right) (T=37°C).
REFERENCES
[1] Special issues: Chem. Soc. Rev, 2009 38,
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44 (2011), 957;. I. Imaz et al., Chem. Comm.,
47 (2011), 7287.
[3] P. Horcajada et al., Angew. Chem. Int. Ed.,
2006, 118, 6120; P. Horcajada et al., Nature
Mater. 9 (2010), 172.
[4] C. Gaudin et al., Micropor. Mesopor. Mater.,
2012 157, 124 ; D. Cunha et al., J. Mater.
Chem. B, 1(8) (2013), 1101.
[5] E.Touitou et al., J. Pharm. Sci., 83 (1994),
1189
105
SOLEIL
HIGHLIGHTS
2013
