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PROXIMA 1 beamline

Research Contents > Beamlines > PROXIMA1

PROXIMA 1 is one of two beamlines at SOLEIL for measurements in macromolecular crystallography (together with PROXIMA 2, currently under construction). PROXIMA 1, operational since March 2008, delivers an intense, parallel and tunable X-ray beam for measurements at high resolution or from large unit cell dimension crystals. The beamline is equipped with a large surface area detector (ADSC Q315r), a 3 circle "kappa" geometry goniostat, with a sample changing robot (ACTOR) to be installed in 2010. The beamline optics permits a range of focussing conditions which can then be adapted to the sample being studied (for example beam focus at sample or detector).

 
First decoding of the mechanism of action of general anaesthetics  
 

Two teams from the Institut Pasteur associated with the CNRS have determined the 3D structure of two general anaesthetics associated with their membrane receptor. This research could be a first step towards designing new compounds, more specific and with fewer side effects. Some of the experimental data was collected on the PROXIMA1 beamline.


 
 
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Beamline description

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Practical informations for users

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 Beamline scientific articles
 

 News :
 
- Elucidation of the 3D structure of chikungunya virus surface proteins
 
- Hepatitis C, when an ultra-virulent strain helps to understand how the virus operates

- S-SAD used to determine the structure of a virus protein

- Research on antibiotic resistant bacteria: a structure solved by the Institut Pasteur and SOLEIL 

When biocrystallography meets high pressure
(november 2006)


 General information:

- Preliminary Project

- Notice

Beamline poster

- PROXIMA2 Beamline

Download diagram of the energy ranges

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