RESEARCH ON OUR SITE
 
 

Infrared in health care

SOLEIL Company Contents > All the news > News 2011 > Infrared in health care

Doctors use a wide range of procedures to screen and diagnose diseases. The thought had probably not crossed their minds, however, that infrared synchrotron radiation might become a complementary tool in this “hunt” for diseases, including those at their earliest stages.

 
To distinguish healthy tissue from diseased tissue, particularly before symptoms appear; make an early diagnosis so as to choose the treatment adapted to the disease; evaluate the effects of the treatment so that the dose administered can be adapted to reduce side effects: all problems that doctors try to solve and for which infrared spectroscopy (IR) could, in some cases, bring answers.

IR spectroscopy image of a steatosic liver tissue section
 
IR spectroscopy image of a steatosic liver tissue section.

 
The technique consists of probing a biological tissue sample with different wavelengths ranging in the IR region.
Above, Paul Dumas, in charge of SMIS beamline.

Easy and simple to set up, the technique consists of probing a biological tissue sample with different wavelengths ranging in the IR region. Each type of molecule that makes up the tissue vibrates at a specific frequency. When the wavelength of the light matches one of the vibration frequencies of the molecule, this light is partially absorbed. The range of wavelengths absorbed composes a spectrum, then providing a key to follow the biocomposition of this tissue and its changes.

The decoding of molecular assemblies and their modifications can also reveal, very early on, abnormal composition of the tissue, or the changes induced by a treatment. This approach has been developed on the SMIS beamline at SOLEIL and the medical community is gradually becoming more aware of its potential. 

 
Contact :
paul.dumas@synchrotron-soleil.fr

 

Three examples
of application :

1 From steatosis
to cancer, via
cirrhosis:

infrared spectroscopy reveals
the specific traits of these liver
diseases from their earliest
stages of development. 

2 Renal calculi:
by ascertaining the composition
of the microcrystals that
make up the calculi, IR
spectroscopy allows the cause
of the disease to be diagnosed
and the appropriate treatment
to be chosen for the patient. 

3 Cancerous cells
of the blood, the
lung or the brain:

through a follow-up with IR
spectroscopy, it is possible
to fine-tune the treatment
that annihilates these
cells, by a combination of
visible light radiation and
medication. 

Accueil