DISCO beamline

Research Contents / Beamlines / Ligne de lumière DISCO au synchrotron SOLEIL

DISCO is a VUV to visible beamline dedicated to biochemistry, chemistry and cell biology. The spectral region is optimised between 60 and 700 nm with conservation of the natural polarization of the light.

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Kidney biopsy studies: a combination of several techniques that improves their accuracy

A new step towards more accurate diagnosis for severe or acute renal failure just has been achieved. In a recent study published in Comptes Rendus Chimie, scientists combined field effect scanning electron microscopy, deep UV fluorescence, Raman spectroscopy and both classical and synchrotron radiation Fourier Transform Infrared spectroscopy to take a special look to crystal-containing kidney biopsies.  [Full story]

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Tryptophan and gold nanoparticles: A winning duo for deep ultraviolet imaging of microbial cells

Researchers from the University of Belgrade successfully demonstrated the utility of tryptophan-functionalized gold nanoparticles as fluorescent probes for imaging of microbial cells. In the study, published in the Colloids and Surfaces B: Biointerfaces, the spatial distribution of hybrid nanoparticles has been determined within individual Escherichia coli cells using deep ultraviolet (DUV) fluorescence imaging, a high spatial resolution microscopy technique. [Full story]

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Beamline notice

DISCO offers three experimental endstations to the scientific communities: SRCD (circular dichroism using synchrotron radiation), APEX (ionisation experiment at atmospheric pressure) and DUV imaging.

Scientific opportinities | Technical data | Team

Users practical informations

DISCO receive users since septembre 09 on three endstations. Using UV synchrotorn radiation, man can observe biomolecules localization, structural changes and interactions in solution, in living cells or in tissues.
Manuals | Communitiess | Lexicon | Links

Science à DISCO

The in-house researches of the DISCO Team concern the interactions of light with biomolecules. They are funded by ANR, Région Centre and PRES UniverSud.
Thèmes de recherche | Financements

 Beamline scientific articles


- A new method to identify protein secondary structure and fold

- Deep photodynamic therapy: a nanoflash-light to activate drugs in solid tumors

- Radiotherapy : a new method to localize unlabeled nanoparticles in tumor cells

- DISCO - SWING : Increased stability of mutant proteins may be responsible for neurodegenerative disease ?

- How to break sugars molecules with light, and what for?

All DISCO news

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Users informations

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of the microscopes

Beamline decription